Sunday, January 22, 2017

Acute liver failure

What happens in acute liver failure?


Acute liver failure  is a deteriorating of liver functions that results in:

  1. Coagulopathy, usually with an international normalized ratio (INR) of greater than 1.5. Causes: impaired liver protein synthesis.
  2.  Encephalopathy - because of impaired ammonia clearance.
  3. Hypoglycemia - because of impaired glyconeogenese.
  4. Jaundice- impaired bilirubin metabolism
  5. Lactic acidosis - impaired lactate clearance. 
  6. Ascites - impaired albumin synthesis 



No comments:

Post a Comment